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The Vital Role of Magnesium in the Body

  • Writer: Rebecca Nolan Harris, PhD
    Rebecca Nolan Harris, PhD
  • Jun 12
  • 2 min read

Magnesium acts as a cofactor for over 300 enzymatic reactions in the body. It is crucial for:

  • Energy Production: Assists in the synthesis of ATP, the primary energy currency of cells.

  • Nerve and Muscle Function: Regulates nerve transmission and muscle contraction.

  • Bone Health: Approximately 60% of the body's magnesium is stored in bones, contributing to their structural integrity.

  • DNA and Protein Synthesis: Essential for the synthesis of genetic material and proteins.


Deficiency in magnesium can disrupt these processes, potentially leading to muscle cramps, mental disorders, osteoporosis, and heart disease.


🥦 Dietary Recommendations and Sources

The Recommended Dietary Allowance (RDA) for magnesium varies by age and sex:

  • Men: 400–420 mg/day

  • Women: 310–320 mg/day

  • Pregnant women require slightly more, around 350 mg/day.


Rich dietary sources of magnesium include:

  • Green Leafy Vegetables: Spinach, Swiss chard

  • Whole Grains: Brown rice, oats, barley (processed grains have significantly less bioavailable magnesium)

  • Nuts and Seeds: Almonds, cashews, hazelnuts

Despite the availability of magnesium-rich foods, many individuals do not meet their daily requirements, making supplementation a consideration for some.


👵 Special Considerations for Older Adults

Individuals over 50 are at increased risk of magnesium deficiency due to factors like decreased dietary intake and impaired absorption. It's advisable for older adults to:

  • Consume Magnesium-Rich Foods: Incorporate a variety of magnesium-containing foods into their diet.

  • Supplement Wisely: Consider a multivitamin/mineral supplement that includes magnesium, but avoid exceeding 350 mg/day from supplements without medical consultation, especially if kidney function is compromised.


🤰 Magnesium in Pregnancy

During pregnancy, magnesium supports fetal development and may help prevent complications such as preeclampsia and eclampsia. Intravenous magnesium sulfate is commonly used in obstetric care to prevent seizures associated with these conditions. Pregnant women should aim for an intake of approximately 350 mg/day.



⚠️ Risks of Deficiency and Excess

Magnesium deficiency can lead to various health issues, including:

  • Cardiovascular Problems: Increased risk of hypertension and heart disease.

  • Bone Disorders: Higher susceptibility to osteoporosis.

  • Metabolic Issues: Impaired insulin sensitivity, leading to type 2 diabetes.

While magnesium toxicity from food sources is rare, excessive intake from supplements can cause adverse effects such as diarrhea, nausea, and abdominal cramping. The Tolerable Upper Intake Level (UL) for supplemental magnesium is set at 350 mg/day.


✅ Conclusion

Magnesium is indispensable for maintaining overall health, influencing various bodily functions from energy production to bone integrity. Ensuring adequate intake through a balanced diet rich in green leafy vegetables, whole grains, and nuts is the best approach. For those unable to meet their needs through diet alone, supplementation may be beneficial, but it's essential to consult with a healthcare provider to avoid potential risks associated with excessive intake.


Linus Pauling Institute. (n.d.). Magnesium. Oregon State University. https://lpi.oregonstate.edu/mic/minerals/magnesium

 
 
 

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