GLP-1 Medications and Magnesium: How Float Therapy Can Help
- Rebecca Nolan Harris, PhD

- Oct 17
- 2 min read
If you're taking GLP-1 medications like Ozempic, Wegovy, or Mounjaro, you may have experienced some of their common side effects: nausea, vomiting, and diarrhea. While these medications are transforming diabetes management and weight loss treatment, they can also create an unexpected challenge—magnesium depletion.
The GLP-1 and Magnesium Connection
GLP-1 receptor agonists work by slowing gastric emptying and reducing appetite, but the gastrointestinal side effects can interfere with nutrient absorption.
Research published in the Journal of Clinical Endocrinology & Metabolism has shown that chronic diarrhea and vomiting can lead to electrolyte imbalances, including magnesium deficiency (Rehfeld et al., 2021). Magnesium is crucial for over 300 enzymatic reactions in your body, including muscle function, nerve transmission, blood sugar control, and bone health.
Symptoms of low magnesium can include muscle cramps, fatigue, irregular heartbeat, and mood changes—issues that can compound the already challenging adjustment period when starting GLP-1 therapy.
Enter Float Therapy: A Unique Magnesium Boost
Float therapy, also known as sensory deprivation or REST (Restricted Environmental Stimulation Therapy), involves floating effortlessly in a tank filled with approximately 1,000 pounds (our tanks have 1,500 pounds) of dissolved Epsom salt (magnesium sulfate). The high concentration of magnesium creates a buoyant environment where you float weightlessly.
But here's the bonus: research suggests that magnesium can be absorbed through the skin. A study from the University of Birmingham found that soaking in Epsom salt baths raised blood magnesium levels in participants (Rosanoff, 2010). During a typical 60-90 minute float session, your skin is in constant contact with this magnesium-rich solution, potentially helping to replenish depleted stores through transdermal absorption.
Beyond magnesium absorption, float therapy offers additional benefits that may be particularly valuable for those on GLP-1 medications: stress reduction, improved sleep quality, and decreased muscle tension—all documented in research published in BMC Complementary Medicine and Therapies (Kjellgren et al., 2014).
Important Safety Considerations
Do NOT use float therapy if you:
Are currently experiencing diarrhea or active gastrointestinal distress
Have open wounds or recent surgical incisions
Have uncontrolled epilepsy
Are under the influence of drugs or alcohol
Have severe skin conditions or infections
The contraindication for active diarrhea is particularly important for GLP-1 users. Diarrhea already causes dehydration and electrolyte loss; the high-salt environment of a float tank can worsen dehydration. Wait until GI symptoms have resolved before booking a float session.
The Bottom Line
While float therapy shows promise as a complementary approach to maintaining healthy magnesium levels, it shouldn't replace medical advice or treatment. If you're experiencing persistent side effects from GLP-1 medications, always consult your healthcare provider. They may recommend magnesium supplementation, dietary changes, or medication adjustments.
For those who are good candidates, float therapy offers a relaxing, potentially beneficial way to support your body's magnesium needs while enjoying deep relaxation.

References:
Kjellgren, A., et al. (2014). Beneficial effects of treatment with sensory isolation in flotation-tank as a preventive health-care intervention. BMC Complementary Medicine and Therapies, 14(1), 417.
Rehfeld, J. F., et al. (2021). Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. Journal of Clinical Endocrinology & Metabolism, 106(7), 1875-1892.
Rosanoff, A. (2010). Magnesium supplements: An update. Nutrition Today, 45(3), 132-136.
This article is for informational purposes only and does not constitute medical advice. Always consult with your healthcare provider before starting any new wellness practice, especially if you're taking prescription medications.




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